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Workshops and Conferences

 

 

     Workshop on Innovative Study Designs and Methods for Developing, Testing

and Implementing Behavioral Interventions to Improve Health (April 2-3, 2014)

 

Post Workshop Slides and Key Articles

 NIH-sponsored Workshop a Success!

Workshop on Innovative Study Designs and Methods for Developing, Testing and Implementing Behavioral Interventions to Improve Health

In this NIH-sponsored Workshop, experts from the behavioral, biostatistical and clinical communities reviewed the utility of new, innovative and potentially more efficient study designs and methods to develop, optimize, test and implement behavioral interventions for behavioral risk factors (e.g., adherence, diet, physical activity, smoking). The format of the Workshop involved presentations and discussions focused mainly on the development and preliminary testing of behavioral interventions on Day 1, with an emphasis on later-stages of development, including testing and implementation of interventions within clinical and community contexts, on Day 2.

 Workshop Panels, Presenters, & Moderators

Speakers and Moderators (click here)

Speakers and Moderators Bios (click here)

Agenda (click here)

Attendees (click here)

 

Day 1:

8:15 AM: NHLBI Perspective: The Need for Creative New Methods in Clinical Research -- Michael Lauer, M.D., Director, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute

                Slides (click here)

                Key article 1: Time for a Creative Transformation of Epidemiology in the United States

Key article 2: Transforming Clinical Trials in Cardiovascular Disease -Mission Critical for Health and Economic Well-being

Key article 3: Eliminating the “expensive” adjective for clinical trials

8:45 AM: Developing and Optimizing Behavioral Treatments to Prevent and Treat Disease -- Susan Czajkowski, Ph.D., National Heart, Lung, and Blood Institute

                Slides (click here)

9:00-4:40: Panels (see details below)

 Day 1, Panel 1

9:00 AM   Panel 1:  Novel Techniques for Defining the Intervention and its Targets -- Moderator:  Christine Hunter, Ph.D., National Institute of Diabetes and Digestive and Kidney Diseases

n  Using “human-centered” design to develop better behavioral interventions -- Silvia Vergani, IDEO

       Slides (click here)

       Key article: Hybrid Insights: Where the Quantitative Meets the Qualitative

n  Behavioral Event Modeling: Identifying and utilizing key inflection points to promote health behavior change -- Brian Wansink, Ph.D., Cornell University

        Slides (click here)

        Key article 1: Behavioral Event Modeling: Identifying and Altering the Antecedents of Action

                Key article 2: Leveraging Inside Sources of Consumer Insights

n  Analyzing patient-provider communication in clinical contexts to identify novel behavior change targets -- April Carcone, Ph.D., Wayne State University

        Slides (click here)

Key article 1: Provider Communication Behaviors that Predict Motivation to Change in Black Adolescents with Obesity

                Key article 2: Analysis of Behavioral Streams

 

 Day 1, Panel 2

10:50 AM  Panel 2:  Intervention Development and Preliminary Testing:  Within-subjects and Small-N Studies

Moderator: Stacey FitzSimmons, Ph.D., Center for Scientific Review

n  Single-case experimental designs- Bethany Raiff, Ph.D., Rowan University

        Slides (click here)

        Key article 1: Single-Case Experimental Designs to Evaluate Novel Technology-Based Health Interventions

Key article 2: Optimizing behavioral health interventions with single-case designs: from development to dissemination

n  Modeling individual trajectories: Subject specific coding for population parameter estimates of treatment effects- Thomas Templin, Ph.D., Wayne State University

        Slides (click here)

        Key article: Analyzing Data from Single-Case Designs Using Multilevel Models: New Applications and Some Agenda Items for Future Research

n  Three techniques for rigorous analysis of intensive within-person experiments- Ty Ridenour, Ph.D., Research Triangle Institute

        Slides (click here)             

        Key article: Toward Rigorous Idiographic Research in Prevention Science: Comparison between Three

                Analytic Strategies for Testing Preventive Intervention in Very Small Samples

 Day 1, Panel 3

1:20 PM  Panel 3:  Study Designs for Refining, Tailoring and Optimizing Interventions I - Moderator: Laura Lee Johnson, Ph.D., National Center for Complementary and Alternative Medicine

n  The Multiphase Optimization Strategy (MOST): A new approach to building effective and efficient behavioral interventions- Kari Kugler, Ph.D., The Pennsylvania State University

        Slides (click here)

        Key article: The Multiphase Optimization Strategy for Engineering Effective Tobacco Use Interventions

n  Bayesian estimation for dose-finding studies - Yuan Ji, Ph.D., University of Chicago

       Slides (click here)

Key article 1: A modified toxicity probability interval method for dose-finding trials

Key article 2: Modified Toxicity Probability Interval Design: A Safer and More Reliable Method than the 3+3 Design for Practical Phase I Trials 

 Day 1, Panel 4

2:50 PM  Panel 4:  Study Designs for Refining, Tailoring and Optimizing Interventions II- Moderator: William Riley, Ph.D., National Cancer Institute

n   Adaptive Interventions:  From SMART to Just-in-Time Adaptive Interventions (JITAI)- Inbal (Billie) Nahum-Shani, Ph.D., University of Michigan

        Slides (click here)

        Key article 1: Experimental Design and Primary Data Analysis Methods for Comparing Adaptive Interventions

Key article 2: Q-Learning: A Data Analysis Method for Constructing Adaptive Interventions

Key article 3: A “SMART” Design for Building Individualized Treatment Sequences

n   Designing user-centered just-in-time adaptive interventions- Pedja Klasnja, Ph.D., University of Michigan

        Slides (click here)

n  Personalizing Behavioral Interventions using Mobile Sensing- Tanzeem Choudhury, Ph.D., Cornell University

        Slides (click here)

        Key article: Tracking Mental Well-Being: Balancing Rich Sensing and Patient Needs  

n   Application of JITAI to substance abuse research- David Gustafson, Ph.D., Univer of Wisconsin at Madison

        Slides (click here)

        Key article: A Smartphone Application to Support Recovery From Alcoholism -A Randomized Clinical Trial

 

 Day 1, Commentary and Additional Considerations Panel

4: 40 PM   Developing and Optimizing Behavioral Interventions: Commentary and Additional Considerations

Moderator: Robert Kaplan, Ph.D., Director, NIH Office of Behavioral and Social Sciences Research

n  Mario Stylianou, Ph.D, National Heart, Lung, and Blood Institute

        Slides (click here)

        Key article: Advances in and Limitations of Up-and-down Methodology: A Précis of Clinical Use, Study Design, and Dose Estimation in Anesthesia Research

n Bonnie Spring, Ph.D., Northwestern University

Key article 1: Multiple Behavior Changes in Diet and Activity: A Randomized Controlled Trial Using Mobile Technology

Key article 2: Integrating Technology into Standard Weight Loss Treatment: A Randomized Controlled Trial

Slides (click here)

                 

 2010 Workshop

 

 NIH-Sponsored Workshop, 2010

Participants were leading basic, translational and intervention development researchers from biomedical and behavioral science fields, including Investigators from ORBIT (Obesity Related Behavioral Intervention Development Trials), experts in basic science discovery and idea generation, and researchers specializing in the design, implementation, and analysis of observational, qualitative, experimental, and behavioral clinical trials research.

 

TRANSLATING IDEAS INTO INTERVENTIONS:

The Process of Developing Behavioral Interventions

December 6-7, 2010

 

Post Workshop Summary Information and Slides

 

 2010 Workshop Information

  Workshop Agenda
  Workshop Speaker and Presenter List
  Workshop Speaker Bios
  Workshop Summary Booklet

 2010 Workshop Presentation

  Linda M. Collins: Efficient Experimental Designs For Examining The Effects Of Individual Intervention Components
  Susan Czajkowski: The ORBIT Model: A Phased Approach to Behavioral Intervention Development
  Leonard H. Epstein: Translating Basic Behavioral Science into Clinical Interventions for Childhood Obesity
  Zorina Galis: Innovation in Life Sciences Research: What can we learn from the biotech and biomedical industries?
  Maria M. Llabre: Synthesis of Methodology Panel
  Deborah H. Olster: NIH Opportunities in Basic & Translational Behavioral Research
  Lisa Onken: The Stage Model of Intervention Development: A Bidirectional + Translational Conceptual Framework
  Michael W. Otto: Paradigm Shifts: Linking Discovery to Intervention
  Lynda H. Powell: Links Among Stage of Intervention Development, Design, and Analysis
  June Stevens: Translating Ideas into Interventions
  Brian Wansink: Designing Interventions that Stick: Behavioral Event Modeling

 Day 2

Day 2:

8:15 AM  Summary of Day 1 and Introduction to Day 2

§  Bonnie Spring, Ph.D., Northwestern University

§  Sylvie Naar-King, Ph.D., Wayne State University

§  Kate Stoney, Ph.D., National Heart, Lung, and Blood Institute

    Slides (click here)

8:30 AM  The NIH Office of Disease Prevention: Encouraging Innovative and Improved Approaches to Prevention Science- David Murray, Ph.D., Director, NIH Office of Disease Prevention

           Slides (click here)

9:00 AM  Behavioral Intervention Research: From Efficacy to Implementation- Kate Stoney, Ph.D., NHLBI

           Slides (click here)

9:15-1:30: Panels

 Day 2, Panel 5

9:15 AM  Panel 5:  Innovative Approaches to Improve the Reach, Delivery and Impact of Behavioral

Interventions- Moderator: Patricia Mabry, Ph.D., NIH Office of Disease Prevention

n  The application of social network analysis to health behavior interventions- Douglas Luke, Ph.D., Washington University in St. Louis

        Slides (click here)

Key article 1: Network Analysis in Public Health: History, Methods, and Applications

Key article 2: Network Interventions

n  Complex systems modeling for behavioral research- Ross Hammond, Ph.D., Brookings Institution

Key article 1: Complex Systems Modeling for Obesity Research

Key article 2: A systems science perspective and transdisciplinary models for food and nutrition security

n  Harnessing “small data” for personalized health promotion - Deborah Estrin, Ph.D., Cornell NYC Tech

        Slides (click here)

Key article 1: Making sense of mobile health data: An open architecture to improve individual and

population level health

        Key article 2: Viewpoint: small data, where n=me. Seeking personalized data-derived insights from analysis of our digital traces.

 Day 2, Panel 6

12:00 PM  Panel 6:  Harnessing Existing Resources to Test and Implement Behavioral Interventions - Moderator:  Wendy Weber, N.D., Ph.D., M.P.H., National Center for Complementary and Alternative Medicine

n  Conducting multifaceted behavioral pragmatic trials within integrated health care systems-

Lynn DeBar, Ph.D., Kaiser Permanente Center for Health Research

Slides (click here)

Key article: A primary care-based interdisciplinary team approach to the treatment of chronic pain utilizing a pragmatic clinical trials framework

n  Leveraging EHR’s in large simple trials of behavioral interventions- Elsie Taveras, M.D., Mass General Hospital for Children

        Slides (click here)

        Key article 1: Provider Perspectives on Electronic Decision Supports for Obesity Prevention

Key article 2: Rationale and design of the STAR randomized controlled trial to accelerate adoption of childhood obesity comparative effectiveness research

n  Partnering with industry in the testing and implementation of behavioral interventions:  Lessons from the Hopkins-Healthways collaboration- Janelle Coughlin, Ph.D., John Hopkins School of Medicine

        Slides (click here)

        Key article: Comparative Effectiveness of Weight-Loss Interventions in Clinical Practice

 Day 2, Commentary and Additional Considerations Panel

1:30 PM  Testing and Implementing Behavioral Interventions:  Commentary and Additional Considerations- Moderator:  Peter Kaufmann, Ph.D., National Heart, Lung, and Blood Institute

n    Ken Kleinman, Ph.D., Harvard Medical School

n    Sylvie Naar-King, Ph.D., Wayne State University    

          Slides (click here)

      Key article 1: Developing a Measure of Therapist Adherence to Contingency Management: An 

      Application of the Many-Facet Rasch Model

      Key article 2: Toward the Effective and Efficient Measurement of Implementation Fidelity

2:20 PM  Summary and Wrap-up- Bonnie Spring, Ph.D. and Sylvie Naar-King, Ph.D.